Sienna Medical Plaza
Missouri City, TX
Space Available
2nd Floor Space Available
$36/SF/Year
Medical
Triple Net (NNN)
Floor 2
18,400 SF
2nd Floor Space Available
18,400 SF
$36/SF/Year
Medical
Triple Net (NNN)
Floor 2
18,400 SF contiguous second-floor medical office above MD Anderson Cancer Center in newly delivered Class A Sienna Medical Plaza. Elevator-served with strong 4:1,000 parking ratio and Highway 6 visibility. Ideal for specialty, imaging, oncology support, women’s health, or referral-based practices seeking institutional identity and built-in patient synergy in Fort Bend County’s fastest-growing corridor.
Sienna Medical Plaza
Summary
- 2nd Floor 18,400 SF
- Medical Office
- Rent $36 SF
- NNN $11.42 SF
- TI $40+ Pending Credit
- Delivery NOW
- Elevator Yes
- Parking 4:1000
- Ceiling Ht 10'
- Wet Sprinkeled Class A
Sienna Medical Plaza is a newly delivered, two-story, 36,800 SF Class A medical office building strategically positioned along Highway 6 in the heart of the Sienna master-planned community in Missouri City, Texas. The property is purpose-built for healthcare and anchored by MD Anderson Cancer Center, which occupies the entire first floor, immediately establishing the building as a recognized medical destination within Fort Bend County.
The available opportunity consists of the full 18,400 SF second floor, offering a contiguous, efficient floor plate designed to accommodate specialty medical, imaging, infusion, oncology support, women’s health, surgical consult, therapy, and other referral-based healthcare providers. Elevator-served and fully sprinklered, the building provides institutional quality construction and professional lobby access, delivering the identity and functionality today’s medical operators require.
Sienna is one of the fastest-growing master-planned communities in the Houston MSA, with significant residential density and strong household incomes surrounding the site. The property benefits from direct exposure and access along Highway 6, a primary north-south arterial serving Missouri City and greater Fort Bend County. This corridor continues to experience sustained population growth, creating long-term demand for healthcare services and specialty providers.
The presence of MD Anderson on-site creates immediate referral synergy, daily patient traffic, and long-term stability for complementary medical users. Opportunities to lease directly above a nationally recognized healthcare institution within a newly constructed, Class A facility are rare in this submarket


